SCULPT™ START – Take the first step toward advanced body transformation with our premium physician-guided program designed to target stubborn body fat while supporting lean muscle and metabolic efficiency.

SCULPT™ — The Science of Next-Generation Metabolic Transformation

Featuring Retatrutide | Advanced Triple-Hormone Research

Beyond appetite control. Exploring the future of metabolic health.

What Is SCULPT™?

SCULPT™ is the MyTrueSelf.fit product name associated with retatrutide, a peptide being studied for its remarkable potential in weight management, metabolic regulation, and obesity treatment.

Retatrutide is one of the most exciting developments in modern metabolic research. Unlike traditional approaches that focus primarily on reducing appetite, retatrutide targets three different hormone receptors involved in hunger, blood sugar regulation, energy balance, and metabolism.

Retatrutide belongs to a new generation of compounds known as triple hormone receptor agonists.

Its three-target mechanism has produced substantial weight reductions in clinical trials, making it a promising candidate for future obesity treatment.

How Does Retatrutide Work?

Retatrutide activates three important hormone receptors simultaneously:

1. GLP-1 — Appetite and Fullness Regulation

GLP-1 helps regulate appetite, supports feelings of fullness, and slows gastric emptying.

By acting on this pathway, retatrutide may reduce hunger and help people consume fewer calories.

2. GIP — Blood Sugar and Metabolic Regulation

GIP is a hormone involved in the body's response to food and the regulation of insulin.

Activating the GIP receptor alongside GLP-1 may enhance metabolic effects and improve blood glucose regulation.

3. Glucagon — Energy Balance

Glucagon has an important role in regulating glucose production and energy metabolism.

Retatrutide's activity at the glucagon receptor may contribute to increased energy expenditure, although the precise contribution of this pathway to long-term weight loss is still being investigated.

Together, these three pathways offer a distinctive approach to metabolic treatment that goes beyond appetite regulation alone.

What Makes Retatrutide Different From Tirzepatide?

Both compounds are being studied or used in the field of metabolic medicine, but their mechanisms differ.

The additional glucagon receptor activity makes retatrutide scientifically distinctive. However, this does not automatically establish that it is safer or more effective than tirzepatide for every individual.

What Have Clinical Studies Revealed?

Retatrutide has produced striking results in controlled clinical studies.

In Phase 3 TRIUMPH-1 trial, participants without diabetes receiving the highest studied treatment dose achieved an average 28.3% reduction in body weight over 80 weeks, under the trial's efficacy analysis.

In the Phase 3 TRIUMPH-2 study involving people with obesity or overweight and type 2 diabetes, participants achieved average weight reductions of up to approximately 20.8% over 80 weeks, according to the reported efficacy analysis.

These outcomes demonstrate the potential of the retatrutide molecule for addressing obesity and related metabolic conditions.

However, these are clinical trial results, not guaranteed outcomes. They cannot be used as evidence that SCULPT™ itself delivers the same benefits.

What Are Researchers Investigating?

Retatrutide is being evaluated for several potential clinical applications:

• Obesity management: Helping people living with obesity achieve clinically meaningful reductions in body weight.

• Appetite and satiety regulation: Understanding its influence on hunger, fullness, and food consumption.

• Type 2 diabetes: Examining effects on blood glucose and HbA1c.

• Metabolic health: Studying changes in waist measurements and cardiometabolic risk factors.

• Obesity-related complications: Investigating possible benefits for conditions such as obstructive sleep apnea, knee osteoarthritis, and metabolic liver disease.

These areas represent ongoing scientific investigation, not approved indications.

How Is Retatrutide Being Administered?

In clinical trials, retatrutide is being investigated as a once-weekly subcutaneous injection, administered under the skin according to carefully monitored research protocols.

Understanding the Safety Considerations

Retatrutide's potential benefits must be considered alongside its risks.

Commonly reported adverse effects in clinical studies include nausea, vomiting, diarrhoea, constipation, and other gastrointestinal symptoms.

People who are pregnant, planning pregnancy, have diabetes, or have significant medical conditions should not experiment with unapproved retatrutide products.

A New Direction in Metabolic Science

The future of obesity management may involve more than controlling hunger. Scientists are increasingly exploring how multiple hormonal pathways influence appetite, insulin sensitivity, body weight, and overall metabolic function.

Retatrutide represents an important part of that scientific progress.

At MyTrueSelf.fit, our vision is to make emerging wellness science easier to understand, helping people make informed decisions about their health while respecting the importance of medical evidence, product quality, and regulatory approval.

SCULPT™ | Retatrutide

Three hormone pathways. One promising scientific breakthrough. A new frontier in metabolic medicine.